Clinical Essentials

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David C. Dale, M.D., F.A.C.P., University of Washington Medical Center School of Medicine

1. ON BEING A PHYSICIAN
   David C. Dale, M.D., F.A.C.P., University of Washington School of Medicine, and Daniel D. Federman, M.D., M.A.C.P., Harvard Medical School
         
   
   
2. CONTEMPORARY ETHICAL AND SOCIAL ISSUES IN MEDICINE
   Christine K. Cassel, M.D., M.A.C.P., American Board of Internal Medicine, and University of Pennsylvania, Ruth Purtilo, Ph.D., Massachusetts General Hospital Institute of Health Professions
         
   
   
3. REDUCING RISK OF INJURY AND DISEASE
   Harold C. Sox, Jr., M.D., M.A.C.P., Annals of Internal Medicine
         
   
   
4. DIET AND EXERCISE
   Harvey B. Simon, M.D., F.A.C.P., Harvard Medical School, Massachusetts Institute of Technology, and Massachusetts General Hospital
         
   
   
5. ADULT PREVENTIVE HEALTH CARE
   Mark Helfand, M.D., Oregon Health and Science University
         
   
   
6. OCCUPATIONAL MEDICINE
   Mark R. Cullen, M.D., Yale University School of Medicine, and Linda Rosenstock, M.D., M.P.H., F.A.C.P., University of California, Los Angeles, School of Public Health
         
   
   
7. HEALTH ADVICE FOR INTERNATIONAL TRAVELERS
   Peter F. Weller, M.D., F.A.C.P., Harvard Medical School and Beth Israel Deaconess Medical Center
         
   
   
8. QUANTITATIVE ASPECTS OF CLINICAL DECISION MAKING
   Brian Haynes, M.D., Ph.D., M.A.C.P., McMaster University Health Sciences Centre, and Harold C. Sox, Jr., M.D., M.A.C.P., Annals of Internal Medicine
         
   
   
9. PALLIATIVE MEDICINE
   Cynthia Pan, M.D., Mt. Sinai School of Medicine
         
   
   
10. SYMPTOM MANAGEMENT IN PALLIATIVE MEDICINE
    Maria Torroella Carney, M.D., Mt. Sinai School of Medicine, and Jennifer Rhodes-Kropf, M.D., Albert Einstein College of Medicine of Yeshiva University
          
    
    
11. MANAGEMENT OF PSYCHOSOCIAL ISSUES IN TERMINAL ILLNESS
    Jennifer Rhodes-Kropf, M.D., Mt. Sinai School of Medicine, and Ned H. Cassem, M.D., F.A.C.P., Harvard Medical School and Massachusetts General Hospital
          
    
    
12. COMPLEMENTARY AND ALTERNATIVE MEDICINE
    Bimal H. Ashar, M.D., F.A.C.P., Johns Hopkins University School of Medicine, and Michael E. Vaezi, M.D., Ph.D., M.Sc. (Epi.), Vanderbilt University School of Medicine
          
    
    
13. PERFORMANCE MEASUREMENT IN CLINICAL PRACTICE
    Stephen D. Persell, M.D., M.P.H., Northwestern University Feinberg School of Medicine, David W. Baker, M.D., M.P.H., F.A.C.P., Northwestern University Feinberg School of Medicine, and Kevin B. Weiss, M.D., M.P.H., F.A.C.P., Northwestern University Feinberg School of Medicine
          

1. Cardiovascular Medicine

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Raymond J. Gibbons, M.D., The Mayo Clinic

1. APPROACH TO THE CARDIOVASCULAR PATIENT
   Catherine M. Otto, M.D., University of Washington School of Medicine, and David M. Shavelle, M.D., Harbor-UCLA Medical Center
         
   
   
2. HEART FAILURE
   Mariell Jessup, M.D., F.A.C.P., University of Pennsylvania Medical School and Hospital of the University of Pennsylvania
         
   
   
3. HYPERTENSION
   Gary L. Schwartz, M.D., F.A.C.P., Mayo Medical School and Mayo Clinic, and Sheldon G. Sheps, M.D., F.A.C.P., Mayo Medical School and Mayo Clinic
         
   
   
4. ATRIAL FIBRILLATION
   Anthony Aizer, M.D., New York University School of Medicine, and Valentin Fuster, M.D., Ph.D., Mount Sinai School of Medicine
         
   
   
5. SUPRAVENTRICULAR TACHYCARDIA
   Melvin M. Scheinman, M.D., University of California, San Francisco, School of Medicine, and Sirisha Sundara, M.D., University of California, San Francisco, School of Medicine
         
   
   
6. VENTRICULAR ARRHYTHMIAS
   Jonathan J. Langberg, M.D., Emory University School of Medicine and Emory University Hospital, and David B. DeLurgio, M.D., Emory University School of Medicine and Emory Crawford Long Hospital
         
   
   
7. PACEMAKER THERAPY
   Nazem W. Akoum, M.D., F.A.C.P., University of Utah School of Medicine, Jonathan Lowy, M.D., St. Joseph’s Hospital/North Cascade Cardiology, Bellingham, Washington, and Roger A. Freedman, M.D., University of Utah School of Medicine
         
   
   
8. ACUTE MYOCARDIAL INFARCTION
   Peter B. Berger, M.D., Duke University Medical Center, and James L. Orford, M.B., Ch.B., M.P.H., Mayday University Hospital, London
         
   
   
9. CHRONIC STABLE ANGINA
   Paul R. Sutton, M.D., Ph.D., F.A.C.P., University of Washington School of Medicine, and Stephan D. Fihn, M.D., M.P.H., F.A.C.P., University of Washington School of Medicine
         
   
   
10. UNSTABLE ANGINA AND NON–ST SEGMENT ELEVATION MYOCARDIAL INFARCTION
    Joel Kupersmith, M.D., F.A.C.P., Vetern Affairs, Washington DC, and Amish Raval, M.D., Georgetown University School of Medicine
          
    
    
11. VALVULAR HEART DISEASE
    Ronan J. Curtin, M.D., M.Sc., Cleveland Clinic Foundation, and Brian P. Griffin, M.D., The Cleveland Clinic Foundation
          
    
    
12. DISEASES OF THE AORTA
    Kim A. Eagle, M.D., F.A.C.P., University of Michigan Health System, and William F. Armstrong, M.D., University of Michigan Medical School and University of Michigan Healthcare System
          
    
    
13. DISEASES OF THE PERICARDIUM, CARDIAC TUMORS, AND CARDIAC TRAUMA
    E. William Hancock, M.D., F.A.C.P., Stanford University School of Medicine
          
    
    
14. CARDIOMYOPATHIES
    [See Chapter II.]
    
    
    
15. CONGENITAL HEART DISEASE
    Heather L. Bartlett, M.D., Assistant Professor of Pediatrics and Director, Pediatric Cardiology Fellowship Program, University of Iowa, Larry T. Mahoney, M.D., University of Iowa College of Medicine, and David J. Skorton, M.D., University of Iowa Hospitals and Clinics
          
    
    
16. PERIPHERAL ARTERIAL DISEASE
    Mark A. Creager, M.D., Harvard Medical School and Brigham and Women's Hospital
          
    
    
17. CARDIAC TUMORS
    [See Chapter XIII.]
    
    
    
18. VENOUS THROMBOEMBOLISM
    Jack Hirsch, M.D., F.A.C.P., McMaster University Faculty of Health Sciences, and Clive Kearon, M.B., Ph.D., McMaster University and Henderson General Hospital, Hamilton Health Sciences
          
    
    

2. Dermatology

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Mark Lebwohl, M.D., Mount Sinai School of Medicine

1. CUTANEOUS MANIFESTATIONS OF SYSTEMIC DISEASES
   Mark Lebwohl, M.D., Mount Sinai School of Medicine
         
   
   
2. PAPULOSQUAMOUS DISORDERS
   Elizabeth A. Abel, M.D., Stanford University School of Medicine
         
   
   
3. PSORIASIS
   Elizabeth A. Abel, M.D., Stanford University School of Medicine, and Mark Lebwohl, M.D., Mount Sinai School of Medicine
         
   
   
4. ECZEMATOUS DISORDERS, ATOPIC DERMATITIS, AND ICHTHYOSES
   Seth R. Stevens, M.D.,Director, Global Medical Affairs, Amgen, Inc., Kevin D. Cooper, M.D., Professor and Chair, Department of Dermatology, Case Western Reserve University School of Medicine, and Kefei Kang, M.D., Associate Professor of Dermatology, Case Western Reserve University School of Medicine
         
   
   
5. CONTACT DERMATITIS AND RELATED DISORDERS
   James S. Taylor, M.D., The Cleveland Clinic Foundation
         
   
   
6. CUTANEOUS ADVERSE DRUG REACTIONS
   Neil H. Shear, M.D., F.A.C.P., University of Toronto Faculty of Medicine and Sunnybrook and Women's College Health Science Centre, Sandra Knowles, B.Sc.Pharm., Sunnybrook and Women's College Health Science Centre, and Lori Shapiro, M.D., University of Toronto Faculty of Medicine and Sunnybrook and Women's College Health Science Centre
         
   
   
7. FUNGAL, BACTERIAL, AND VIRAL INFECTIONS OF THE SKIN
   Jan V. Hirschmann, M.D., University of Washington School of Medicine and Puget Sound Veterans Affairs Medical Center
         
   
   
8. PARASITIC INFESTATIONS
   Elizabeth A. Abel, M.D, Stanford University School of Medicine
         
   
   
9. VESICULOBULLOUS DISEASES
   Elizabeth A. Abel, M.D., Stanford University School of Medicine, and Jean-Claude Bystryn, M.D., New York University School of Medicine and NYU Kaplan Comprehensive Cancer Center
         
   
   
10. MALIGNANT CUTANEOUS TUMORS
    Allan C. Halpern, M.D., Joan and Sanford I. Weill Medical College of Cornell University and Memorial Sloan-Kettering Cancer Center, and Patricia L. Myskowski, M.D., Joan and Sanford I. Weill Medical College of Cornell University and Memorial Sloan-Kettering Cancer Center
          
    
    
11. BENIGN CUTANEOUS TUMORS
    Elizabeth A. Abel, M.D., Stanford University School of Medicine
          
    
    
12. ACNE VULGARIS AND ROSACEA
    James Q. Del Rosso, D.O., University of Nevada School of Medicine
          
    
    
13. DISORDERS OF HAIR
    David A. Whiting, M.D., F.A.C.P., University of Texas Southwestern Medical Center at Dallas and Baylor Hair Research and Treatment Center
          
    
    
14. DISEASES OF THE NAIL
    James Q. Del Rosso, D.O., University of Nevada School of Medicine, and C. Ralph Daniel III, M.D., University of Mississippi School of Medicine
          
    
    
15. DISORDERS OF PIGMENTATION
    Pearl E. Grimes, M.D., University of California Los Angeles David Geffen School of Medicine
          



16. APPROACH TO THE DIAGNOSIS OF SKIN DISEASE
    Robert T. Brodell, M.D., Northeastern Ohio Universities College of Medicine and Case Western Reserve University School of Medicine, and Stephen E. Helms, M.D., Northeastern Ohio Universities College of Medicine and Case Western Reserve University School of Medicine
          

3. Endocrinology

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D. Lynn Loriaux, M.D., Ph.D., M.A.C.P., Oregon Health and Science University

1. THYROID
   Paul W. Ladenson, M.D., F.A.C.P., John Hopkins University School of Medicine
         
   
   
2. TESTES AND TESTICULAR DISORDERS
   Peter J. Snyder, M.D., Professor of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine
         
   
   
3. OVARY
   The information in this chapter has been moved to Section 16, Women's Health.
   
   
4. THE ADRENAL
   D. Lynn Loriaux, M.D., Ph.D., M.A.C.P., Oregon Health and Science University
         
   
   
5. PITUITARY
   Shlomo Melmed, M.D., F.A.C.P., Cedars-Sinai Medical Center
         
   
   
6. DISEASES OF CALCIUM METABOLISM AND METABOLIC BONE DISEASE
   Silvio E. Inzucchi, M.D., Yale University School of Medicine, and Elizabeth H. Holt, M.D., Ph.D., Yale University School of Medicine Chief, Endocrinology, VA-CT Healthcare
         
   
   
7. GENETICS FOR THE CLINICIAN
   Robb Moses, M.D., Oregon Health and Science University School of Medicine, and Jone E. Sampson, M.D., Oregon Health Sciences University School of Medicine
         
   
   
8. GENETIC DIAGNOSIS AND COUNSELING
   Roberta A. Pagon, M.D., University of Washington School of Medicine
         
   
   
9. HYPOGLYCEMIA
   F. John Service, M.D., Ph.D., F.A.C.P., Mayo Medical School
         



10. OBESITY
    Jonathan Q. Purnell, M.D., Oregon Health and Science University
          

4. Gastroenterology

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Mark Feldman, M.D., F.A.C.P., University of Texas Southwestern Medical School at Dallas and Presbyterian Hospital of Dallas

1. ESOPHAGEAL DISORDERS
   Stuart Jon Spechler, M.D., Dallas VA Medical Center
         
   
   
2. PEPTIC ULCER DISEASES
   Mark Feldman, M.D., F.A.C.P., University of Texas Southwestern Medical School at Dallas and Presbyterian Hospital of Dallas, and Michael S. Le, M.D., University of Mississippi Medical Center
         
   
   
3. DIARRHEAL DISEASES
   Lawrence R. Schiller, M.D., F.A.C.P., University of Texas Southwestern Medical Center at Dallas and Baylor University Medical Center
         
   
   
4. INFLAMMATORY BOWEL DISEASES
   Stephen B. Hanauer, M.D., F.A.C.P., University of Chicago Pritzker School of Medicine and University of Chicago Hospital
         
   
   
5. DISEASES OF THE PANCREAS
   Peter Draganov, M.D., University of Florida College of Medicine, and Chris E. Forsmark, M.D., F.A.C.P., University of Florida College of Medicine
         
   
   
6. GALLSTONES AND BILIARY TRACT DISEASE
   Kimberly M. Persley, M.D., University of Texas Southwestern Medical Center at Dallas, and Rajeev Jain, M.D., F.A.C.P., University of Texas Southwestern Medical Center at Dallas
         
   
   
7. ACUTE VIRAL HEPATITIS
   Marlyn Mayo, M.D., University of Texas Southwestern Medical Center at Dallas
         
   
   
8. CHRONIC HEPATITIS
   Peter F. Malet, M.D., F.A.C.P., University of Texas Southwestern Medical Center at Dallas
         
   
   
9. CIRRHOSIS OF THE LIVER
   Ramón Bataller, M.D., Liver Unit, Institut de Malalties Digestives i Metabòliques, Hospital Clinic, Barcelona, Catalonia, Spain, and Pere Ginès, Liver Unit, Institut de Malalties Digestives i Metabòliques, Hospital Clinic, Barcelona, Catalonia, Spain
         
   
   
10. GASTROINTESTINAL BLEEDING
    Elizabeth Rajan, M.D., Mayo Medical Center, and David A. Ahlquist, M.D., Mayo Medical Center
          
    
    
11. DISEASES PRODUCING MALABSORPTION AND MALDIGESTION
    Charles M. Mansbach II, M.D., University of Tennessee, Memphis, College of Medicine
          
    
    
12. DIVERTICULOSIS, DIVERTICULITIS, AND APPENDICITIS
    William V. Harford, Jr., M.D., F.A.C.P., University of Texas Southwestern Medical Center at Dallas and Dallas Veterans Affairs Medical Center
          
    
    
13. ENTERAL AND PARENTERAL NUTRITION
    Brant Lutsi, M.D., Northwestern University Feinberg School of Medicine,and Alan Buchman, M.D., M.S.P.H., F.A.C.P., Northwestern University Feinberg School of Medicine
          
    
    
14. GASTROINTESTINAL MOTILITY DISORDERS
    Henry P. Parkman, M.D., Temple University School of Medicine
          
    
    
15. LIVER AND PANCREAS TRANSPLANTATION
    Robert L. Carithers, Jr., M.D., F.A.C.P., University of Washington School of Medicine, and James D. Perkins, M.D., University of Washington School of Medicine
          

5. Hematology

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David C. Dale, M.D., F.A.C.P., University of Washington School of Medicine

1. APPROACH TO HEMATOLOGIC DISORDERS
   David C. Dale, M.D., F.A.C.P., University of Washington School of Medicine
         
   
   
2. RED BLOOD CELL FUNCTION AND DISORDERS OF IRON METABOLISM
   Gary M. Brittenham, M.D., Columbia University College of Physicians and Surgeons
   Robert T Means, Jr., M.D., F.A.C.PProfessor & Senior Associate Chair, Department of Internal Medicine, University of Kentucky College of Medicine, and Interim Director, Markey Cancer Center
         
   
   
3. ANEMIA: PRODUCTION DEFECTS
   Stanley L. Schrier, M.D., F.A.C.P., Stanford University School of Medicine
         
   
   
4. HEMOGLOBINOPATHIES AND HEMOLYTIC ANEMIAS
   Stanley L. Schrier, M.D., F.A.C.P., Stanford University School of Medicine,
   Elizabeth A.Price, MD, MPH Clinical Instructor, Department of Medicine, Division of Hematology, Stanford University School of Medicine
         
   
   
5. THE POLYCYTHEMIAS
   Virginia C. Broudy, M.D., F.A.C.P., University of Washington School of Medicine and Harborview Medical Center
         
   
   
6. DISORDERS OF HEMOSTASIS AND COAGULATION
   [See Chapters XII through XIV.]
   
   
   
7. NONMALIGNANT DISORDERS OF LEUKOCYTES
   David C. Dale, M.D., F.A.C.P., University of Washington School of Medicine
         
   
   
8. THE LEUKEMIAS AND THE MYELOPROLIFERATIVE DISORDERS
   [See Section 12, Chapters XVI and XVII.]
   
   
   
9. MULTIPLE MYELOMA AND RELATED SERUM PROTEIN DISORDERS
   [The information in this chapter is being incorporated into other chapters.]
   
   
   
10. TRANSFUSION MEDICINE
    Harvey G. Klein, M.D., National Institutes for Health
          
    
    
11. HEMATOPOIETIC CELL TRANSPLANTATION
    Frederick R. Appelbaum, M.D., University of Washington School of Medicine and Fred Hutchinson Cancer Research Center
          
    
    
12. HEMOSTASIS AND ITS REGULATION
    Lawrence L. K. Leung, M.D., Stanford University School of Medicine, and VA Palo Alto Health Care Systems
          
    
    
13. PLATELET AND VASCULAR DISORDERS
    Lawrence L. K. Leung, M.D., Stanford University School of Medicine, and VA Palo Alto Health Care Systems
          
    
    
14. THROMBOTIC DISORDERS
    Lawrence L. K. Leung, M.D., Stanford University School of Medicine, and VA Palo Alto Health Care Systems
          
    
    
15. COAGULATION DISORDERS
    Lawrence L. K. Leung, M.D., Stanford University School of Medicine, and VA Palo Alto Health Care Systems
          

6. Immunology/Allergy

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John P. Atkinson, M.D., F.A.C.P., Washington University School of Medicine

1. ORGANS AND CELLS OF THE IMMUNE SYSTEM
   John R. David, M.D., Harvard School of Public Health and Harvard Medical School, and Cox Terhorst, Ph.D., Harvard Medical School and Beth Israel Deaconess Medical Center
         
   
   
2. INNATE IMMUNITY
   M. Kathryn Liszewski, M.D., B.A., Washington University School of Medicine, St. Louis, Wayne M. Yokoyama, M.D., Washington University School of Medicine, St. Louis, and John P. Atkinson, M.D., F.A.C.P., Washington University School of Medicine, St. Louis Barnes-Jewish Hospital,
         
   
   
3. ADAPTIVE IMMUNITY: ANTIGENS, ANTIBODIES, AND T CELL AND B CELL RECEPTORS
   Cox Terhorst, Ph.D., Harvard Medical School and Beth Israel Deaconess Medical Center, and John R. David, M.D., Harvard School of Public Health and Harvard Medical School
         
   
   
4. CELL-CELL INTERACTIONS, CYTOKINES, AND CHEMOKINES IN IMMUNE RESPONSE MECHANISMS
   John R. David, M.D., Harvard School of Public Health and Harvard Medical School, and Cox Terhorst, Ph.D., Harvard Medical School and Beth Israel Deaconess Medical Center
         
   
   
5. ADAPTIVE IMMUNITY: HISOMPATIBILITY ANTIGENS AND IMMUNE RESPONSE GENES
   Edgar L. Milford, M.D., Harvard Medical School and Brigham and Women's Hospital, and Charles B. Carpenter, M.D., Harvard Medical School and Brigham and Women's Hospital
         
   
   
6. ORCHESTRATING THE IMMUNE RESPONSE
   [This chapter is currently in preparation.]
   
   
7. IMMUNOGENETICS OF DISEASE
   Edgar L. Milford, M.D., Harvard Medical School and Brigham and Women's Hospital, and Charles B. Carpenter, M.D., Harvard Medical School and Brigham and Women's Hospital
         
   
   
8. DEFICIENCIES IN IMMUNOGLOBULINS AND CELL-MEDIATED IMMUNITY
   Fred S. Rosen, M.D., Harvard Medical School and Center for Blood Research
         
   
   
9. IMMUNOLOGIC TOLERANCE AND AUTOIMMUNITY
   Paul Anderson, M.D., Ph.D., Harvard Medical School and Brigham and Women's Hospital
         
   
   
10. ALLERGIC RESPONSE
    Pamela J. Daffern, M.D., Medical College of Virginia at Virginia Commonwealth University, and Lawrence B. Schwartz, M.D., Ph.D., Medical College of Virginia at Virginia Commonwealth University
          
    
    
11. DIAGNOSTIC AND THERAPEUTIC PRINCIPLES IN ALLERGY
    Mitchell H. Grayson, M.D., Washington University School of Medicine, St. Louis , and Phillip E. Korenblat, M.D., F.A.C.P., Washington University School of Medicine
          
    
    
12. ALLERGIC RHINITIS, CONJUNCTIVITIS, AND SINUSITIS
    Raymond G. Slavin, M.D., M.A.C.P., St. Louis University School of Medicine
          
    
    
13. URTICARIA, ANGIOEDEMA, AND ANAPHYLAXIS
    Vincent S. Beltrani, M.D., University of Medicine and Dentistry of New Jersey
          



14. DRUG ALLERGIES
    Mark S. Dykewicz, M.D., F.A.C.P., St. Louis University School of Medicine and St. Louis University Hospital, and Heather Gray, M.D., St. Louis University School of Medicine and St. Louis University Hospital
          



15. ALLERGIC REACTIONS TO HYMENOPTERA
    David B. K. Golden, M.D., F.A.C.P., Johns Hopkins University School of Medicine
          



16. FOOD ALLERGIES
    A. Wesley Burks, M.D., Duke University Medical Center
          

7. Infectious Disease

---

David C. Dale, M.D., F.A.C.P., University of Washington School of Medicine

1. INFECTIONS DUE TO GRAM-POSITIVE COCCI
   Dennis L. Stevens, M.D., Ph.D., F.A.C.P., University of Washington School of Medicine
         
   
   
2. TUBERCULOSIS
   Michael K. Leonard, Jr., M.D., Emory University School of Medicine, and Henry M. Blumberg, M.D., F.A.C.P., Emory University School of Medicine
         
   
   
3. INFECTIONS DUE TO NEISSERIA
   Jeanne M. Marrazzo, M.D., M.P.H., F.A.C.P., University of Washington School of Medicine and Jo Hofmann, M.D., Washington State Department of Health
         
   
   
4. INFECTIONS DUE TO GRAM-POSITIVE BACILLI
   Frederick S. Southwick, M.D., F.A.C.P., University of Florida College of Medicine
         
   
   
5. ANAEROBIC INFECTIONS
   Anthony W. Chow, M.D., F.A.C.P., F.R.C.P.C., University of British Columbia Faculty of Medicine
         
   
   
6. SYPHILIS AND NONVENEREAL TREPONEMATOSES
   Michael Augenbraun, M.D., F.A.C.P., State University of New York Downstate Medical Center
         
   
   
7. LYME DISEASE AND OTHER SPIROCHETAL ZOONOSES
   David C. Tompkins, M.D., State University of New York at Stony Brook, and Benjamin J. Luft, M.D., F.A.C.P., State University of New York at Stony Brook
         
   
   
8. INFECTIONS DUE TO ESCHERICHIA COLI AND OTHER ENTERIC GRAM-NEGATIVE BACILLI
   Michael S. Donnenberg, M.D., University of Maryland School of Medicine
         
   
   
9. ENTERIC INFECTIONS DUE TO CAMPYLOBACTER, SALMONELLA, SHIGELLA, YERSINIA, VIBRIO, AND HELICOBACTER
   Marcia B. Goldberg, M.D., Massachusetts General Hospital and Harvard Medical School
         
   
   
10. INFECTIONS DUE TO HAEMOPHILUS, MORAXELLA, LEGIONELLA, BORDETELLA, AND PSEUDOMONAS
    Shawn J. Skerrett, M.D., University of Washington School of Medicine
          
    
    
11. INFECTIONS DUE TO BRUCELLA, FRANCISELLA, YERSINIA PESTIS, AND BARTONELLA
    W. Conrad Liles, M.D., Ph.D., F.A.C.P., University of Washington School of Medicine
          
    
    
12. MYCOPLASMA INFECTIONS
    R. Doug Hardy, M.D., University of Texas Southwestern Medical Center at Dallas
          
    
    
13. DISEASES DUE TO CHLAMYDIA
    Walter E. Stamm, M.D., F.A.C.P., University of Washington School of Medicine
          
    
    
14. ANTIMICROBIAL THERAPY
    Timothy H. Dellit, M.D., University of Washington School of Medicine, and Thomas M. Hooton, M.D., F.A.C.P., University of Washington School of Medicine,
          
    
    
15. SEPTIC ARTHRITIS
    Brian F. Mandell, M.D., Ph.D., F.A.C.P., The Cleveland Clinic Foundation
          
    
    
16. OSTEOMYELITIS
    Layne O. Gentry, M.D., F.A.C.P., Baylor College of Medicine and St. Luke's Episcopal Hospital
          
    
    
17. INFECTIONS DUE TO RICKETTSIA, EHRLICHIA, AND COXIELLA
    Daniel J. Sexton, M.D., F.A.C.P, Duke University Medical Center
          
    
    
18. INFECTIVE ENDOCARDITIS
    David. T. Durack, M.D., D.Phil., F.A.C.P., Duke University School of Medicine, and Adolf W. Karchmer, M.D., F.A.C.P., Harvard Medical School
          
    
    
19. BACTERIAL INFECTIONS OF THE UPPER RESPIRATORY TRACT
    Harvey B. Simon, M.D., F.A.C.P., Harvard Medical School, Massachusetts Institute of Technology, and Massachusetts General Hospital
          
    
    
20. PNEUMONIA AND OTHER PULMONARY INFECTIONS
    Harvey B. Simon, M.D., F.A.C.P., Harvard Medical School, Massachusetts Institute of Technology, and Massachusetts General Hospital
          
    
    
21. PERITONITIS AND INTRA-ABDOMINAL ABSCESSES
    W. Conrad Liles, M.D., Ph.D., University of Washington School of Medicine, and E. Patchen Dellinger, M.D., University of Washington School of Medicine
          
    
    
22. VAGINITIS AND SEXUALLY TRANSMITTED DISEASES
    Matthew R. Golden, M.D., M.P.H., University of Washington School of Medicine
          
    
    
23. URINARY TRACT INFECTIONS
    Kalpana Gupta, M.D., M.P.H., Boston Veterans Administration Health Care System, and Walter E. Stamm, M.D., F.A.C.P., University of Washington School of Medicine
          
    
    
24. HYPERTHERMIA, FEVER, AND FEVER OF UNDETERMINED ORIGIN
    Harvey B. Simon, M.D., F.A.C.P., Harvard Medical School, Massachusetts Institute of Technology, and Massachusetts General Hospital
          
    
    
25. RESPIRATORY VIRAL INFECTIONS
    Frederick G. Hayden, M.D., F.A.C.P., University of Virginia School of Medicine, and Michael G. Ison, M.D., M.Sc., Northwestern University Feinburg School of Medicine
          
    
    
26. HERPESVIRUS INFECTIONS
    Martin S. Hirsch, M.D., Harvard Medical School and Massachusetts General Hospital
          
    
    
27. ACUTE VIRAL CENTRAL NERVOUS SYSTEM DISEASES
    [See Section 11, Chapter XVI.]
    
    
    
28. ENTERIC VIRAL INFECTIONS
    Nino Khetsuriani, M.D., Ph.D., Centers for Disease Control and Prevention, and Umesh D. Parashar, M.D., M.P.H., Centers for Disease Control and Prevention
          
    
    
29. MEASLES, MUMPS, RUBELLA, PARVOVIRUS, AND POXVIRUS
    Martin S. Hirsch, M.D., Harvard Medical School and Massachusetts General Hospital
          
    
    
30. SEPSIS
    Steven LaRosa, M.D., Brown University School of Medicine, and Steven M. Opal, M.D., Brown Medical School
          
    
    
31. VIRAL ZOONOSES
    Duane J. Gubler, Sc.D., Colorado State University, Johns Hopkins University School of Public Health, and Centers for Disease Control and Prevention, and Lyle R. Petersen, M.D., M.P.H., Centers for Disease Control and Prevention
          
    
    
32. HUMAN RETROVIRAL INFECTIONS OTHER THAN HIV INFECTION
    Mark A. Beilke, M.D., and Christy Barrios, Ph.D., Medical College of Wisconsin
          
    
    
33. HIV AND AIDS
    Christopher J. Hoffmann, M.D., M.P.H., M.Sc., Johns Hopkins University School of Medicine, and Joel E. Gallant, M.D., M.P.H., Johns Hopkins University School of Medicine
          
    
    
34. PROTOZOAN INFECTIONS
    Wesley C. Van Voorhis, M.D., Ph.D., F.A.C.P., University of Washington School of Medicine
          
    
    
35. HELMINTHIC INFECTIONS
    Wesley C. Van Voohis, M.D., Ph.D., F.A.C.P., University of Washington School of Medicine, and Peter F. Weller, M.D., F.A.C.P., Harvard Medical School and Beth Israel Deaconess Medical Center
          
    
    
36. BACTERIAL INFECTIONS OF THE CENTRAL NERVOUS SYSTEM
    Jan V. Hirschmann, M.D., University of Washington School of Medicine and Puget Sound VA Medical Center
          
    
    
37. MYCOTIC INFECTIONS
    Carol A. Kauffman, M.D., F.A.C.P., University of Michigan Medical School
          
    
    
38. MYCOTIC INFECTIONS IN THE COMPROMISED HOST
    Jo-Anne H. Young, M.D., F.A.C.P., University of Minnesota Medical School
          



39. INFECTIONS DUE TO MYCOBACTERIUM LEPRAE AND NONTUBERCULOUS MYCOBACTERIA
    Michael K. Leonard, Jr., M.D., Emory University School of Medicine, and Henry M. Blumberg, M.D., Emory University School of Medicine
          

8. Interdisciplinary Medicine

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David C. Dale, M.D., F.A.C.P., University of Washington School of Medicine

1. MANAGEMENT OF POISONING AND DRUG OVERDOSE
   Kent R. Olson, M.D., F.A.C.P., University of California, San Francisco, Schools of Medicine and Pharmacy, and San Francisco Division, California Poison Control System,
   Manish M. Patel, M.D., Emory University School of Medicine
   Timothy J. Wiegand, MD Assistant Adjunct Professor of Medicine, University of California, San Francisco, and The California Poison Control System, San Francisco Division
         
   
   
2. BITES AND STINGS
   Lawrence M. Lewis, M.D., Washington University School of Medicine, Mark D. Levine, M.D., Washington University School of Medicine, and William H. Dribben, M.D., Washington University School of Medicine
         
   
   
3. CARDIAC RESUSCITATION
   Terry J. Mengert, M.D., University of Washington School of Medicine
         
   
   
4. PREOPERATIVE ASSESSMENT
   Michael F. Lubin, M.D., F.A.C.P., Emory University School of Medicine
         
   
   
5. BIOTERRORISM
   Jeffrey S. Duchin, M.D., University of Washington School of Medicine, Department of Public Health, Seattle and King County, Washington
         
   
   
6. [This chapter is currently in preparation, and the title is to be determined.]
   
   
7. [This chapter is currently in preparation, and the title is to be determined.]
   
   
8. ASSESSMENT OF THE GERIATRIC PATIENT
   Helen K. Edelberg, M.D., Mount Sinai School of Medicine
         
   
   
9. MANAGEMENT OF COMMON CLINICAL DISORDERS IN GERIATRIC PATIENTS
   Robert M. Palmer, M.D., F.A.C.P., The Cleveland Clinic Foundation
         
   
   
10. REHABILITATION OF GERIATRIC PATIENTS
    Stephanie Studenski, M.D., M.P.H., University of Pittsburgh School of Medicine, and Cynthia J. Brown, M.D., P.T., University of Alabama at Birmingham
    Susan E. Hardy, MD, PhD Assistant Professor, Department of Medicine, University of Pittsburgh School of Medicine, and Medical Director, Centers for Rehabilitation, Pittsburgh
          

9. Metabolism

---

D. Lynn Loriaux, M.D., Ph.D., M.A.C.P., Oregon Health Sciences University

1. TYPE 1 DIABETES MELLITUS
   Saul Genuth, M.D., F.A.C.P., Case Western Reserve University School of Medicine
         
   
   
2. TYPE 2 DIABETES MELLITUS
   Matthew C. Riddle, M.D., Oregon Health and Science University, and Saul Genuth, M.D., F.A.C.P., Case Western Reserve University School of Medicine
         
   
   
3. COMPLICATIONS OF DIABETES MELLITUS
   Mark E. Molitch, M.D., F.A.C.P., Northwestern University Feinberg School of Medicine, and Saul Genuth, M.D., F.A.C.P., Case Western Reserve University School of Medicine
         
   
   
4. GESTATIONAL DIABETES MELLITUS
   Amy Aronovitz, M.D., Northwestern University Feinberg School of Medicine, and Boyd E. Metzger, M.D., Northwestern University Feinberg School of Medicine
         
   
   
5. SECONDARY FORMS OF DIABETES MELLITUS
   Ildiko Lingvay, M.D., M.P.H., University of Texas Southwestern Medical School at Dallas and Philip Raskin, M.D., F.A.C.P.,University of Texas Southwestern Medical School at Dallas
         
   
   
6. DIAGNOSIS AND TREATMENT OF DYSLIPIDEMIA
   John D. Brunzell, M.D., F.A.C.P., University of Washington School of Medicine, and R. Alan Failor, M.D., University of Washington School of Medicine
         
   
   
7. THE PORPHYRIAS
   Shigeru Sassa, M.D., Ph.D., Rockefeller University, and Attallah Kappas, M.D., F.A.C.P., Rockefeller University
         

10. Nephrology

---

William L. Henrich, M.D., F.A.C.P., University of Maryland School of Medicine

1. RENAL FUNCTION AND DISORDERS OF WATER AND SODIUM BALANCE
   Richard H. Sterns, M.D., F.A.C.P., University of Rochester School of Medicine and Dentistry, Rochester General Hospital, and the Genesee Hospital
         
   
   
2. DISORDERS OF ACID-BASE AND POTASSIUM BALANCE
   Robert M. Black, M.D., University of Massachusetts Medical School and Worcester Medical Center
         
   
   
3. APPROACH TO THE PATIENT WITH RENAL DISEASE
   Biff F. Palmer, M.D., F.A.C.P., University of Texas Southwestern Medical Center at Dallas
         
   
   
4. MANAGEMENT OF CHRONIC KIDNEY DISEASE
   Biff P. Palmer, M.D., F.A.C.P., University of Texas Southwestern Medical Center at Dallas, and Michael K. Hise, M.D., University of Maryland School of Medicine
         
   
   
5. GLOMERULAR DISEASES
   Raimund H. Pichler, M.D., University of Washington School of Medicine, and Stuart J. Shankland, M.D., University of Washington School of Medicine
         
   
   
6. ACUTE RENAL FAILURE
   Mary Jo Shaver, M.D., University of Arkansas for Medical Sciences, and Sadhir V. Shah, M.D., F.A.C.P., University of Arkansas for Medical Sciences
         
   
   
7. VASCULAR DISEASES OF THE KIDNEY
   Abhijit V. Kshirsagar, M.D., M.P.H., University of North Carolina at Chapel Hill School of Medicine, and Ronald J. Falk, M.D., F.A.C.P., University of North Carolina at Chapel Hill School of Medicine
         
   
   
8. TUBULOINTERSTITIAL DISEASES
   Gerald B. Appel, M.D., F.A.C.P., Columbia University College of Physicians and Surgeons and New York Presbyterian Hospital, and Premila Bhat, M.D., Columbia University College of Physicians and Surgeons
         
   
   
9. PHARMACOLOGIC APPROACH TO RENAL INSUFFICIENCY
   Ali J. Olyaei, Pharm. D., Oregon Health and Science University, and William M. Bennett, M.D., M.A.C.P., Northwest Renal Clinic, Legacy Good Samaritan Hospital
   
   Appendix A DRUG THERAPY IN RENAL DISEASE
         
   
   
10. CHRONIC RENAL FAILURE AND DIALYSIS
    Eric P. Cohen, M.D., Medical College of Wisconsin
          
    
    
11. RENAL TRANSPLANTATION
    David K. Klassen, M.D., University of Maryland School of Medicine, and Matthew R. Weir, M.D., F.A.C.P., University of Maryland School of Medicine
          
    
    
12. NEPHROLITHIASIS
    Fuad N. Ziyadeh, M.D., University of Pennsylvania School of Medicine, and Stanley Goldfarb, M.D., F.A.C.P., University of Pennsylvania School of Medicine
          
    
    
13. BENIGN PROSTATIC HYPERPLASIA
    Michael J. Barry, M.D., F.A.C.P., Harvard Medical School and General Medical Unit, Massachusetts General Hospital
          


14. CARDIOVASCULAR DISEASE IN PATIENTS WITH RENAL DISEASE
    Wajeh Y. Qunibi, M.D., University of Texas Health Science Center at San Antonio, William L. Henrich, M.D., M.A.C.P., University of Texas Health Science Center at San Antonio, and Tomas Berl, M.D., F.A.S.N., University of Colorado
          

11. Neurology

---

Jerry S. Wolinsky, M.D., The University of Texas Health Science Center and Hermann Hospital

1. THE DIZZY PATIENT
   David Solomon, M.D., Ph.D., Johns Hopkins University School of Medicine, and Elliot M. Frohman, M.D., Ph.D., University of Texas Southwestern Medical School
         
   
   
2. DISEASES OF THE PERIPHERAL NERVOUS SYSTEM
   Colin H. Chalk, M.D., C.M., Associate Professor, Department of Neurology and Neurosurgery, McGill University and Director, Division of Neurology, Montreal General Hospital
         
   
   
3. DISEASES OF MUSCLE AND THE NEUROMUSCULAR JUNCTION
   Marinos C. Dalakas, M.D., National Institute of Neurological Disorders and Stroke, National Institutes of Health
         
   
   
4. CEREBROVASCULAR DISORDERS
   Scott E. Kasner, M.D., University of Pennsylvania School of Medicine and Hospital of the University of Pennsylvania, and Lewis B. Morgenstern, M.D., University of Michigan Medical Center
         
   
   
5. TRAUMATIC BRAIN INJURY
   Andres M. Salazar, M.D., Oncovir, Inc.
         
   
   
6. NEOPLASTIC DISORDERS
   Jerome B. Posner, M.D., Memorial Sloan-Kettering Cancer Center
         
   
   
7. ANOXIC, METABOLIC, AND TOXIC ENCEPHALOPATHIES
   Michael J. Aminoff, M.D., D.Sc., University of California, San Francisco, School of Medicine
         
   
   
8. HEADACHE
   Randolph W. Evans, M.D., Joan and Sanford I. Weill Medical College of Cornell University